Acquired Immune Deficiency Syndrome also known as AIDS

Since the first cases of AIDS, reported in 1959, came from Africa, this adds to the presumption that this is where the disease originated.

Chimpanzee simian immunodeficiency viruses (SIVs) atomic number 18 rare, and lonesome(prenominal) three cases had previously been identified. The recent discovery of a quaternate case by Dr. Hahn=s team, together with a slender investigation of where each of the apes came from, cleared up some of the details. The patrimonial material of the four chimpanzee SIVs suggests that three of them, including the new one, are closely related. The fourth belongs to a different branch of the SIV family tree.

By analyzing genes from the chimpanzees, Dr. Hahn and her colleagues hold shown that three related SIVs come from a sub-species of chimpanzee that lives in Gabon, Cameroon, and Equatorial Guinea. The fourth virus was found in a second sub-species that lives farther to the east. This species lives in the same part where AIDS was first found in humans. In this region, these animals progress to long been hunted for food, so blood from the carcasses could easily have entered the hunters= bodies through superficial wounds.

Hahn=s free radical showed how, after saltation species on at least three occasions, chi

http://onhealth.com/ch1/briefs/reuters/item.80372.asp

Henderson, C. W. Protease Inhibitors Boost Survival. antiviral drug Weekly November 22, (1999).

The oldest known case of HIV-1 infection was reported in a sailor from Manchester who died of an AIDS illness in 1959, and the authenticity of this case has not been confirmed (Zhu et al, 594-594). This group promulgated a report in Nature in 1998 on an HIV-1 sequence from an African plasma sample from 1959 for which multiple phylogenetic sequence analyses authenticated it as the oldest known HIV-1 infection, and placed its viral sequence near the ancestral node of subtypes B and D in the major gene, indicating that these HIV-1 subtypes and perhaps all new group viruses may have evolved from a single introduction into the African population not long before 1959.

Data from long-run non-progressors - individuals who remain asymptomatic despite HIV infection of 10 years or more - also support this hypothesis. The regulation of low virus load and normal T-cell counts seen in patients handle early with highly active antiretroviral therapy regimens is similar to that seen in long-term non-progressors. Early treatment may improve the viral and immunological setpoints of steady-state latent HIV infection. There is some evidence that early, aggressive treatment is associated with a survival advantage over slow up treatment.

The chimpanzees also carry their version of the virus but it does not make them sick, a fact which may reveal all-important(a) clues about controlling AIDS in humans, since humans touch 98.5 percent of their genes with chimpanzees. A problem which may hamper incoming research is the fact that the chimpanzees are being hunted approximately to extinction, which means hunters may be acquiring different strains of the virus, and a living database of AIDS information may become confounded to researchers.

Zhu, Tuofu, Korber, Bette T., Nahmias, Andre J., Hooper, Edward, Sharp, Paul M., and Ho, David D. An Afric
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